[Methotrexate for rheumatoids]_Efficacy_Effect
There are many rheumatoids implanted in life. Rheumatoid patients are often placed by the sick, especially in rainy weather, because the weather will be cooler and the air will be more, so they will often feel themselves.Joint pain, so for rheumatoid patients, the use of plaster treatment is the best treatment, then is methotrexate effective for rheumatoid rheumatoid arthritis?
The course of rheumatoid arthritis is variable, and some patients ‘disease progresses in a serious direction; others can be naturally relieved; most patients’ conditions change drastically. Rheumatoid arthritis is mainly a joint complication, joint synovial complications occur, and synoviumFlesh and tooth tissue grows at the edges, and the resulting iliac crest destroys the tibia of the joint. The blood vessels slowly expand, and finally all the spine of the joint can be destroyed. This disease cannot be cured by drugs at present, and it can only control its development.
Through a large number of studies, many scholars believe that the early application of methotrexamine in the treatment of rheumatoid arthritis is beneficial for the early control of the disease progression.
In the clinical treatment of rheumatoid arthritis, four types of drugs are often used.
One of the most important is immunosuppressive drugs. One of the most widely used drugs is methotrexate.
Methotrexate is an antifolate metabolism drug.
Now it is mainly used for the treatment of tumors.
Although the mechanism of methotrexate for the treatment of rheumatoid arthritis is not very clear, but because of its direct anti-inflammatory effect, the clinical application is effective, it is easy to use, and it is a serious alternative.With its efficacy, rheumatologists are now attracting more and more attention. It breaks the use of non-steroidal anti-inflammatory drugs or other disease-modifying drugs such as gold preparations and penicillamine treatment.Traditional usage.
Distal multinomial use of small doses of methotrexamidine to treat rheumatoid arthritis.
Generally, the daily service method is used, and it is taken within one week of a week. Those who are more severe or cannot be taken orally can use weekly intravenous shock or intramuscular injection.
Oral into the first injection of 5 mg, gradually increase the amount, the maximum amount does not exceed 30 mg per week, generally 7 per week.
It has the characteristics of rapid action, improved efficacy, and low risk; some patients can improve joint swelling and pain after 1 or 2 applications, usually within 1 month.
The drug works quickly, and it repeats quickly after stopping the drug. Generally, within two weeks after the drug is stopped, the controlled condition will happen quickly.
Therefore, it should be maintained orally when the condition is under control.
It is currently believed that the sustainable application of methotrexate 5?
More than 6 years.
Long-term treatment of methotrexate has been controversial in the past.
Preliminary studies have shown that long-term treatment of methotrexate is both effective and better tolerated than other disease-modifying drugs.